Antibodies that detect NOTCH2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target NOTCH2 in Human, Mouse, Rat, Canine and Chimpanzee samples. Our NOTCH2 polyclonal,...Antibodies that detect NOTCH2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target NOTCH2 in Human, Mouse, Rat, Canine and Chimpanzee samples. Our NOTCH2 polyclonal, recombinant...Antibodies that detect NOTCH2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target NOTCH2 in Human, Mouse, Rat, Canine and Chimpanzee samples. Our NOTCH2 polyclonal, recombinant monoclonal, monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Rat, Mouse and Goat. These antibodies have been verified by Knockdown to confirm specificity to NOTCH2. Find the NOTCH2 antibody that fits your needs. Choose from 1 of 27 NOTCH2 antibodies, which have been validated in experiments with 11 publications and 42 images featured in our data gallery.
Browse primary antibodies for WB, Flow,...
Antibodies that detect NOTCH2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA and Immunoprecipitation. These antibodies target NOTCH2 in Human, Mouse, Rat, Canine and Chimpanzee samples. Our NOTCH2 polyclonal, recombinant monoclonal, monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Rat, Mouse and Goat. These antibodies have been verified by Knockdown to confirm specificity to NOTCH2. Find the NOTCH2 antibody that fits your needs. Choose from 1 of 27 NOTCH2 antibodies, which have been validated in experiments with 11 publications and 42 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved Notch signaling pathway protein. NOTCH2 is a type 1 transmembrane protein with an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. NOTCH2 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Defects in NOTCH2 are the cause of Alagille syndrome type 2 (ALGS2). Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations. There are characteristic facial features and less frequent clinical involvement of the renal and vascular systems.
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