RNF2 Antibodies

Antibodies that detect RNF2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ChIP and Immunocytochemistry. These antibodies target RNF2 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our RNF2 polyclonal,... Antibodies that detect RNF2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ChIP and Immunocytochemistry. These antibodies target RNF2 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our RNF2 polyclonal, recombinant monoclonal and... Antibodies that detect RNF2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ChIP and Immunocytochemistry. These antibodies target RNF2 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our RNF2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. These antibodies have been verified by Knockdown to confirm specificity to RNF2. Find the RNF2 antibody that fits your needs. Choose from 1 of 15 RNF2 antibodies, which have been validated in experiments with 5 publications and 39 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications.... Antibodies that detect RNF2 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, ChIP and Immunocytochemistry. These antibodies target RNF2 in Human, Mouse, Rat, Non-human primate and Bovine samples. Our RNF2 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat and Mouse. These antibodies have been verified by Knockdown to confirm specificity to RNF2. Find the RNF2 antibody that fits your needs. Choose from 1 of 15 RNF2 antibodies, which have been validated in experiments with 5 publications and 39 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

RNF2 (E3 ubiquitin-protein ligase RING2) is a ligase that mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub). Therefore, it plays a central role in histone code and gene regulation. The ligase activity is enhanced by BMI1/PCGF4. H2AK119Ub gives a specific tag for epigeneti transcriptional repression and participates in X chromosome inactivation of female mammals. RNF2 may be involved in the initiation of both imprinted and random X inactivation. RNF2 is also an essential component of a Polycomb group (PcG) multiprotein PRC1-like complex. This complex class is required to maintain the transcriptionally repressive state of many genes including Hox genes throughout development. The PcG PRC1 complex acts via chromatin remodeling and modification of histones and rendering chromatin heritably changed in its expressibility.

同义词

AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; DinG; DinG protein; E3 ubiquitin-protein ligase RING2; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; protein DinG; RING 1B; RING 2; RING finger protein 1B; ring finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; Rnf2

RNF2 Antibodies

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