Product References
Epithelial colonization by gut dendritic cells promotes their functional diversification.
Immunity
Rivera CA,Randrian V,Richer W,Gerber-Ferder Y,Delgado MG,Chikina AS,Frede A,Sorini C,Maurin M,Kammoun-Chaari H,Parigi SM,Goudot C,Cabeza-Cabrerizo M,Baulande S,Lameiras S,Guermonprez P,Reis e Sousa C,Lecuit M,Moreau HD,Helft J,Vignjevic DM,Villablanca EJ,Lennon-Duménil AM
12-1031-82 was used in Flow cytometry/Cell sorting to investigate How tissue-specific cues orchestrate Dendritic cells diversification.
Tue Jan 11 00:00:00 UTC 2022
Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine.
Nature immunology
Li C,Lee A,Grigoryan L,Arunachalam PS,Scott MKD,Trisal M,Wimmers F,Sanyal M,Weidenbacher PA,Feng Y,Adamska JZ,Valore E,Wang Y,Verma R,Reis N,Dunham D,O'Hara R,Park H,Luo W,Gitlin AD,Kim P,Khatri P,Nadeau KC,Pulendran B
12-1031-82 was used in Flow Cytometry to provide insights into the molecular mechanisms by which the BNT162b2 vaccine stimulates immune responses.
Fri Apr 01 00:00:00 UTC 2022
Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes.
iScience
Spath S,Roan F,Presnell SR,Höllbacher B,Ziegler SF
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Fri Sep 16 00:00:00 UTC 2022
TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability.
Mucosal immunology
Ninnemann J,Winsauer C,Bondareva M,Kühl AA,Lozza L,Durek P,Lissner D,Siegmund B,Kaufmann SHE,Mashreghi MF,Nedospasov SA,Kruglov AA
12-1031-82 was used in Flow cytometry/Cell sorting to show how anti-TNF therapy induces mucosal healing by increasing IL-22 availability and implicates new therapeutic opportunities for IBD.
Fri Apr 01 00:00:00 UTC 2022
Mycobacterium tuberculosis infection drives a type I IFN signature in lung lymphocytes.
Cell reports
Akter S,Chauhan KS,Dunlap MD,Choreño-Parra JA,Lu L,Esaulova E,Zúñiga J,Artyomov MN,Kaushal D,Khader SA
12-1031-82 was used in Flow cytometry/Cell sorting to understand and characterizing the transcriptional parameters at a single-cell depth in a highly relevant and reproducible mouse model of TB.
Tue Jun 21 00:00:00 UTC 2022
Sensing plasma membrane pore formation induces chemokine production in survivors of regulated necrosis.
Developmental cell
Wang W,Prokopec JS,Zhang Y,Sukhoplyasova M,Shinglot H,Wang MT,Linkermann A,Stewart-Ornstein J,Gong YN
12-1031-82 was used in Flow cytometry/Cell sorting to find that cells which undergo limited plasma membrane damage from the pore-forming actions of MLKL, GSDMD, perforin, or detergents experience local activation of PKCs through Ca2+ influx at the damage sites.
Mon Jan 24 00:00:00 UTC 2022
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
Science advances
Poh AR,Love CG,Chisanga D,Steer JH,Baloyan D,Chopin M,Nutt S,Rautela J,Huntington ND,Etemadi N,O'Brien M,O'Keefe R,Ellies LG,Macri C,Mintern JD,Whitehead L,Gangadhara G,Boon L,Chand AL,Lowell CA,Shi W,Pixley FJ,Ernst M
12-1031-82 was used in Flow cytometry/Cell sorting to suggest that therapeutic targeting of HCK activity enhances response to immunotherapy by simultaneously stimulating immune cell activation and inhibiting the immunosuppressive tumor microenvironment.
Fri Jun 24 00:00:00 UTC 2022
A molecular atlas of innate immunity to adjuvanted and live attenuated vaccines, in mice.
Nature communications
Lee A,Scott MKD,Wimmers F,Arunachalam PS,Luo W,Fox CB,Tomai M,Khatri P,Pulendran B
12-1031-82 was used in Flow Cytometry to profile the kinetics, transcriptomics and epigenomics of innate immune cells in murine draining lymph nodes following 3M-052-Alum/Ovalbumin immunization.
Thu Jan 27 00:00:00 UTC 2022
Lipid A analog CRX-527 conjugated to synthetic peptides enhances vaccination efficacy and tumor control.
NPJ vaccines
Tondini E,Reintjens NRM,Castello G,Arakelian T,Isendoorn M,Camps M,Vree J,van der Marel GA,Filippov DV,Codee JDC,Ossendorp F
12-1031-82 was used in Flow cytometry/Cell sorting to highlight the potential of CRX-527 as an adjuvant for molecularly defined cancer vaccines, and support the design of adjuvant-peptide conjugates as a strategy to optimize vaccine formulation.
Thu Jun 23 00:00:00 UTC 2022
STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.
Cellular and molecular gastroenterology and hepatology
Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Mon Jan 24 00:00:00 UTC 2022
Sex-specific adipose tissue imprinting of regulatory T cells.
Nature
Vasanthakumar A,Chisanga D,Blume J,Gloury R,Britt K,Henstridge DC,Zhan Y,Torres SV,Liene S,Collins N,Cao E,Sidwell T,Li C,Spallanzani RG,Liao Y,Beavis PA,Gebhardt T,Trevaskis N,Nutt SL,Zajac JD,Davey RA,Febbraio MA,Mathis D,Shi W,Kallies A
12-1031-82 was used in Flow Cytometry to find that sex-specific differences in Treg cells from visceral adipose tissue are determined by the tissue niche in a sex-hormone-dependent manner to limit adipose tissue inflammation.
Sun Mar 01 00:00:00 UTC 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
12-1031 was used in Flow cytometry/Cell sorting to describe a mechanism by which the innate immune system allows rapid quality check of absorbed fluids to avoid intoxication of colonocytes.
Thu Oct 15 00:00:00 UTC 2020
Macrophages Maintain Epithelium Integrity by Limiting Fungal Product Absorption.
Cell
Chikina AS,Nadalin F,Maurin M,San-Roman M,Thomas-Bonafos T,Li XV,Lameiras S,Baulande S,Henri S,Malissen B,Lacerda Mariano L,Barbazan J,Blander JM,Iliev ID,Matic Vignjevic D,Lennon-Duménil AM
12-1031 was used in Flow cytometry/Cell sorting to describe a mechanism by which the innate immune system allows rapid quality check of absorbed fluids to avoid intoxication of colonocytes.
Thu Oct 15 00:00:00 UTC 2020
Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver.
Immunity
Remmerie A,Martens L,Thoné T,Castoldi A,Seurinck R,Pavie B,Roels J,Vanneste B,De Prijck S,Vanhockerhout M,Binte Abdul Latib M,Devisscher L,Hoorens A,Bonnardel J,Vandamme N,Kremer A,Borghgraef P,Van Vlierberghe H,Lippens S,Pearce E,Saeys Y,Scott CL
12-1031 was used in Flow cytometry/Cell sorting to highlight considerable heterogeneity within the macrophage pool and suggest a need for more specific macrophage targeting strategies in metabolic-associated fatty liver disease (MAFLD).
Tue Sep 15 00:00:00 UTC 2020
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
Immunity
Bosteels C,Neyt K,Vanheerswynghels M,van Helden MJ,Sichien D,Debeuf N,De Prijck S,Bosteels V,Vandamme N,Martens L,Saeys Y,Louagie E,Lesage M,Williams DL,Tang SC,Mayer JU,Ronchese F,Scott CL,Hammad H,Guilliams M,Lambrecht BN
12-1031 was used in Flow cytometry/Cell sorting to show that monocyte-derived inflammatory DCs’’ are a mixture of monocyte-derived MCs that have little migratory and APC potential and bona fide pre-cDCderived, CD26-expressing inf-cDC2s that depend on Flt3L but not on GM-CSF.
Tue Jun 16 00:00:00 UTC 2020
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
12-1031 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 UTC 2020
The Cytokine TGF-β Induces Interleukin-31 Expression from Dermal Dendritic Cells to Activate Sensory Neurons and Stimulate Wound Itching.
Immunity
Xu J,Zanvit P,Hu L,Tseng PY,Liu N,Wang F,Liu O,Zhang D,Jin W,Guo N,Han Y,Yin J,Cain A,Hoon MA,Wang S,Chen W
12-1031 was used in Flow cytometry/Cell sorting to investigate the mechanisms underlying itching associated with cutaneous wound healing, focusing on the contribution of soluble factors released during healing.
Tue Aug 18 00:00:00 UTC 2020
Contact-dependent delivery of IL-2 by dendritic cells to CD4 T cells in the contraction phase promotes their long-term survival.
Protein & cell
Tong D,Zhang L,Ning F,Xu Y,Hu X,Shi Y
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Sat Feb 01 00:00:00 UTC 2020
Delayed Akt suppression in the lipopolysaccharide-induced acute lung injury promotes resolution that is associated with enhanced effector regulatory T cells.
American journal of physiology. Lung cellular and molecular physiology
Artham S,Verma A,Alwhaibi A,Adil MS,Manicassamy S,Munn DH,Somanath PR
12-1031 was used in Flow cytometry/Cell sorting to identify a potential target for the treatment of late-stage ALI by promoting resolution through effector Treg-mediated suppression of inflammation.
Wed Apr 01 00:00:00 UTC 2020
Inhibition of the Wnt/β-catenin pathway enhances antitumor immunity in ovarian cancer.
Therapeutic advances in medical oncology
Doo DW,Meza-Perez S,Londoño AI,Goldsberry WN,Katre AA,Boone JD,Moore DJ,Hudson CT,Betella I,McCaw TR,Gangrade A,Bao R,Luke JJ,Yang ES,Birrer MJ,Starenki D,Cooper SJ,Buchsbaum DJ,Norian LA,Randall TD,Arend RC
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Thu Apr 14 00:00:00 UTC 2022
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
12-1031 was used in Flow cytometry/Cell sorting to created a gene expression compendium across 24 distinct human and murine lung and lymph node mononuclear phagocyte (MP), along with human blood and murine spleen MPs, to serve as validation datasets.
Tue Nov 03 00:00:00 UTC 2020
Human and Mouse Transcriptome Profiling Identifies Cross-Species Homology in Pulmonary and Lymph Node Mononuclear Phagocytes.
Cell reports
Leach SM,Gibbings SL,Tewari AD,Atif SM,Vestal B,Danhorn T,Janssen WJ,Wager TD,Jakubzick CV
12-1031 was used in Flow cytometry/Cell sorting to created a gene expression compendium across 24 distinct human and murine lung and lymph node mononuclear phagocyte (MP), along with human blood and murine spleen MPs, to serve as validation datasets.
Tue Nov 03 00:00:00 UTC 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
12-1031 was used in Flow cytometry/Cell sorting to show homeostasis of thymically-derived and peripherally-derived Treg cells is maintained through the balancing of TCR signaling induced transcriptional activity by Bach2.
Tue Jan 14 00:00:00 UTC 2020
Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis.
Nature communications
Sidwell T,Liao Y,Garnham AL,Vasanthakumar A,Gloury R,Blume J,Teh PP,Chisanga D,Thelemann C,de Labastida Rivera F,Engwerda CR,Corcoran L,Kometani K,Kurosaki T,Smyth GK,Shi W,Kallies A
12-1031 was used in Flow cytometry/Cell sorting to show homeostasis of thymically-derived and peripherally-derived Treg cells is maintained through the balancing of TCR signaling induced transcriptional activity by Bach2.
Tue Jan 14 00:00:00 UTC 2020
TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4+ T Cells to Treg.
Cell reports
Dolina JS,Lee J,Griswold RQ,Labarta-Bajo L,Kannan S,Greenbaum JA,Bahia El Idrissi N,Pont MJ,Croft M,Schoenberger SP
12-1031 was used in Flow cytometry/Cell sorting to resolve long-standing questions regarding the conditional requirement for TH amongst pathogens and reveal a remarkable degree of plasticity in the function of CD4+ T cells, which can be quickly converted to Tregin vivo by infection-mediated immune modulation.
Tue Apr 07 00:00:00 UTC 2020
Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells.
Frontiers in immunology
Ko HJ,Hong SW,Verma R,Jung J,Lee M,Kim N,Kim D,Surh CD,Kim KS,Rudra D,Im SH
12-1031 was used in Flow cytometry/Cell sorting to reveal previously underappreciated role of dietary glucose concentration in establishing regulatory properties in intestinal DCs, thereby extending a potential therapeutic module against intestinal inflammation.
Mon Apr 19 00:00:00 UTC 2021
The cis-Regulatory Atlas of the Mouse Immune System.
Cell
Yoshida H,Lareau CA,Ramirez RN,Rose SA,Maier B,Wroblewska A,Desland F,Chudnovskiy A,Mortha A,Dominguez C,Tellier J,Kim E,Dwyer D,Shinton S,Nabekura T,Qi Y,Yu B,Robinette M,Kim KW,Wagers A,Rhoads A,Nutt SL,Brown BD,Mostafavi S,Buenrostro JD,Benoist C
12-1031-82 was used in Flow Cytometry to generate matched epigenome and transcriptome measurements in 86 primary cell types that span the mouse immune system and its differentiation cascade.
Thu Feb 07 00:00:00 UTC 2019
Metabolite-Sensing Receptor Ffar2 Regulates Colonic Group 3 Innate Lymphoid Cells and Gut Immunity.
Immunity
Chun E,Lavoie S,Fonseca-Pereira D,Bae S,Michaud M,Hoveyda HR,Fraser GL,Gallini Comeau CA,Glickman JN,Fuller MH,Layden BT,Garrett WS
12-1031 was used in Flow cytometry/Cell sorting to demonstrate group 3 innate lymphoid cells are regulated by the metabolite-sensing receptor Ffar2.
Tue Nov 19 00:00:00 UTC 2019
Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy.
Nature communications
Rosato PC,Wijeyesinghe S,Stolley JM,Nelson CE,Davis RL,Manlove LS,Pennell CA,Blazar BR,Chen CC,Geller MA,Vezys V,Masopust D
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Mon Feb 04 00:00:00 UTC 2019
CSF1R antagonism limits local restimulation of antiviral CD8+ T cells during viral encephalitis.
Journal of neuroinflammation
Funk KE,Klein RS
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Thu Jan 31 00:00:00 UTC 2019
Direct interaction of whole-inactivated influenza A and pneumococcal vaccines enhances influenza-specific immunity.
Nature microbiology
David SC,Norton T,Tyllis T,Wilson JJ,Singleton EV,Laan Z,Davies J,Hirst TR,Comerford I,McColl SR,Paton JC,Alsharifi M
12-1031 was used in Flow cytometry/Cell sorting to provide an additional explanation for the synergistic pathogenicity of IAV and S. pneumoniae, as well as heralding the prospect of exploiting the phenomenon to develop better vaccine strategies for both pathogens.
Thu Aug 01 00:00:00 UTC 2019
The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response.
eLife
Lavoie S,Conway KL,Lassen KG,Jijon HB,Pan H,Chun E,Michaud M,Lang JK,Gallini Comeau CA,Dreyfuss JM,Glickman JN,Vlamakis H,Ananthakrishnan A,Kostic A,Garrett WS,Xavier RJ
12-1031 was used in Flow cytometry/Cell sorting to unravel the effects of ATG16L1 T300A on the microbiota and immune system, employing a gnotobiotic model using human fecal transfers into ATG16L1 T300A knock in mice.
Tue Jan 22 00:00:00 UTC 2019
Limited Foxp3+ Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8+ T Cell Immunity.
Frontiers in immunology
Araujo Furlan CL,Tosello Boari J,Rodriguez C,Canale FP,Fiocca Vernengo F,Boccardo S,Beccaria CG,Adoue V,Joffre O,Gruppi A,Montes CL,Acosta Rodriguez EV
12-1031 was used in Flow cytometry/Cell sorting to study the role of regulatory T cells during Trypanosoma cruzi infection.
Thu Sep 26 00:00:00 UTC 2019
Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Cell reports
Kirkling ME,Cytlak U,Lau CM,Lewis KL,Resteu A,Khodadadi-Jamayran A,Siebel CW,Salmon H,Merad M,Tsirigos A,Collin M,Bigley V,Reizis B
Tue Jun 19 00:00:00 UTC 2018
Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.
JCI insight
Burman A,Kropski JA,Calvi CL,Serezani AP,Pascoalino BD,Han W,Sherrill T,Gleaves L,Lawson WE,Young LR,Blackwell TS,Tanjore H
12-1031 was used in Flow cytometry/Cell sorting to study the role of hypoxia in lung fibrosis.
Thu Aug 23 00:00:00 UTC 2018
NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer.
Cell
Grinberg-Bleyer Y,Oh H,Desrichard A,Bhatt DM,Caron R,Chan TA,Schmid RM,Klein U,Hayden MS,Ghosh S
12-1031-82 was used in Flow cytometry/Cell sorting to understand the mechanisms governing regulatory T cells homeostasis.
Thu Sep 07 00:00:00 UTC 2017
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.
Immunity
Essig K,Hu D,Guimaraes JC,Alterauge D,Edelmann S,Raj T,Kranich J,Behrens G,Heiseke A,Floess S,Klein J,Maiser A,Marschall S,Hrabĕ de Angelis M,Leonhardt H,Calkhoven CF,Noessner E,Brocker T,Huehn J,Krug AB,Zavolan M,Baumjohann D,Heissmeyer V
12-1031-82 was used in Flow Cytometry to show Roquin-mediated control of PI3K-mTOR signaling prevents autoimmunity by restraining activation and differentiation of conventional T cells and specialization of Treg cells.
Tue Dec 19 00:00:00 UTC 2017
NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.
Nature immunology
Chen L,Wilson JE,Koenigsknecht MJ,Chou WC,Montgomery SA,Truax AD,Brickey WJ,Packey CD,Maharshak N,Matsushima GK,Plevy SE,Young VB,Sartor RB,Ting JP
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Mon May 01 00:00:00 UTC 2017
Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.
The EMBO journal
Kawasaki T,Ito K,Miyata H,Akira S,Kawai T
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Wed Jun 14 00:00:00 UTC 2017
Eosinophils are required to suppress Th2 responses in Peyer's patches during intestinal infection by nematodes.
Mucosal immunology
Strandmark J,Steinfelder S,Berek C,Kühl AA,Rausch S,Hartmann S
12-1031 was used in Flow cytometry/Cell sorting to study whether eosinophils affect the local T-cell and antibody response in the gut-associated lymphoid tissue during enteric infections.
Mon May 01 00:00:00 UTC 2017
Intestinal helminth infection induces highly functional resident memory CD4+ T cells in mice.
European journal of immunology
Steinfelder S,Rausch S,Michael D,Kühl AA,Hartmann S
Wed Feb 01 00:00:00 UTC 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Thu Oct 06 00:00:00 UTC 2016
Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection.
Mucosal immunology
Dudek M,Puttur F,Arnold-Schrauf C,Kühl AA,Holzmann B,Henriques-Normark B,Berod L,Sparwasser T
12-1031 was used in Flow cytometry/Cell sorting to investigate the extent to which MyD88 signaling is required to control S. pneumoniae infection, showing that lung epithelium and myeloid cells cooperate to clear infection.
Thu Sep 01 00:00:00 UTC 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Mon Aug 15 00:00:00 UTC 2016
Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets.
Journal of immunology (Baltimore, Md. : 1950)
Toomer KH,Yuan X,Yang J,Dee MJ,Yu A,Malek TR
12-1031 was used in Flow cytometry/Cell sorting to elucidate the developmental progression and interrelationship of central and effector regulatory T cell subsets.
Sun May 01 00:00:00 UTC 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Wed Jun 15 00:00:00 UTC 2016
Expression of CD11c Is Associated with Unconventional Activated T Cell Subsets with High Migratory Potential.
PloS one
Qualai J,Li LX,Cantero J,Tarrats A,Fernández MA,Sumoy L,Rodolosse A,McSorley SJ,Genescà M
12-1031 was used in Flow cytometry/Cell sorting to find markers associated with non-conventional T cell subsets, including γδ T cells and invariant natural killer T cells.
Thu Mar 16 00:00:00 UTC 2017
Altered lymph node composition in diphtheria toxin receptor-based mouse models to ablate dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
van Blijswijk J,Schraml BU,Rogers NC,Whitney PG,Zelenay S,Acton SE,Reis e Sousa C
12-1031 was used in Flow cytometry/Cell sorting to report that mice in which DTR is expressed on DCs display lymph node hypocellularity and reduced frequency of DCs in the same organs.
Thu Jan 01 00:00:00 UTC 2015
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
12-1031 was used in Flow cytometry/Cell sorting to study how immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Mon Dec 01 00:00:00 UTC 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
12-1031 was used in Flow cytometry/Cell sorting to study how immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Mon Dec 01 00:00:00 UTC 2014
Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Nature medicine
Clatworthy MR,Aronin CE,Mathews RJ,Morgan NY,Smith KG,Germain RN
12-1031 was used in Flow cytometry/Cell sorting to study how immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes.
Mon Dec 01 00:00:00 UTC 2014
Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection.
Journal of virology
Channappanavar R,Fett C,Zhao J,Meyerholz DK,Perlman S
12-1031 was used in Flow cytometry/Cell sorting to determine the factors governing a successful immune response to lethal SARS-CoV challenge.
Wed Oct 01 00:00:00 UTC 2014
CD326(lo)CD103(lo)CD11b(lo) dermal dendritic cells are activated by thymic stromal lymphopoietin during contact sensitization in mice.
Journal of immunology (Baltimore, Md. : 1950)
Ochiai S,Roediger B,Abtin A,Shklovskaya E,Fazekas de St Groth B,Yamane H,Weninger W,Le Gros G,Ronchese F
12-1031 was used in Flow cytometry/Cell sorting to identify a subset of dendritic cells which are highly responsive to cytokine thymic stromal lymphopoietin.
Mon Sep 01 00:00:00 UTC 2014
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Jiao J,Dragomir AC,Kocabayoglu P,Rahman AH,Chow A,Hashimoto D,Leboeuf M,Kraus T,Moran T,Carrasco-Avino G,Friedman SL,Merad M,Aloman C
12-1031 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cells in neutrophil homeostasis, showing a central role in regulation of bone marrow release and survival of neutrophils.
Tue Apr 01 00:00:00 UTC 2014
The NF-κB regulator Bcl-3 governs dendritic cell antigen presentation functions in adaptive immunity.
Journal of immunology (Baltimore, Md. : 1950)
Tassi I,Claudio E,Wang H,Tang W,Ha HL,Saret S,Ramaswamy M,Siegel R,Siebenlist U
12-1031 was used in Flow cytometry/Cell sorting to study the role of Bcl-3 in dendritic cell survival and the generation of adaptive immunity.
Sat Nov 01 00:00:00 UTC 2014
Tumor-promoting role of TGFβ1 signaling in ultraviolet B-induced skin carcinogenesis is associated with cutaneous inflammation and lymph node migration of dermal dendritic cells.
Carcinogenesis
Ravindran A,Mohammed J,Gunderson AJ,Cui X,Glick AB
12-1031 was used in Flow cytometry/Cell sorting to study how TGFβ1 signalling has a tumour-promoting role in UVB-induced skin carcinogenesis, which is mediated in part through its role in UVB-induced migration of dDC and cutaneous inflammation.
Tue Apr 01 00:00:00 UTC 2014
Lung dendritic cells undergo maturation and polarization towards a T helper type 2-stimulating phenotype in a mouse model of asthma: Role of nerve growth factor.
Experimental and therapeutic medicine
Qin Q,Wang Z,Pan P,Cao Z,Xia Q,Tan H,Hu C
Published figure using CD103 (Integrin alpha E) monoclonal antibody (Product # 12-1031-82) in Flow Cytometry
Sat Nov 01 00:00:00 UTC 2014
Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice.
PloS one
Busch M,Westhofen TC,Koch M,Lutz MB,Zernecke A
12-1031 was used in Flow cytometry/Cell sorting to perform a systematic analysis of dendritic cells and their accumulation characteristics during atherogenesis.
Tue Oct 21 00:00:00 UTC 2014
The transcription factor STAT5 is critical in dendritic cells for the development of TH2 but not TH1 responses.
Nature immunology
Bell BD,Kitajima M,Larson RP,Stoklasek TA,Dang K,Sakamoto K,Wagner KU,Kaplan DH,Reizis B,Hennighausen L,Ziegler SF
12-1031 was used in Flow cytometry/Cell sorting to investigate how type-2 immunity is affected by STAT5 transcription factor in dendritic cells.
Mon Apr 01 00:00:00 UTC 2013
Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.
Nature immunology
Satpathy AT,Briseño CG,Lee JS,Ng D,Manieri NA,Kc W,Wu X,Thomas SR,Lee WL,Turkoz M,McDonald KG,Meredith MM,Song C,Guidos CJ,Newberry RD,Ouyang W,Murphy TL,Stappenbeck TS,Gommerman JL,Nussenzweig MC,Colonna M,Kopan R,Murphy KM
12-1031 was used in Flow cytometry/Cell sorting to elucidate the cellular source of essential IL-23 production required for the mucosal response to attaching-and-effacing bacterial infection.
Sun Sep 01 00:00:00 UTC 2013
TGFβ1 overexpression by keratinocytes alters skin dendritic cell homeostasis and enhances contact hypersensitivity.
The Journal of investigative dermatology
Mohammed J,Gunderson AJ,Khong HH,Koubek RD,Udey MC,Glick AB
12-1031 was used in Flow cytometry/Cell sorting to highlight a role for keratinocyte-derived TGFβ1 in dendritic cell trafficking and in the initiation of skin inflammation.
Tue Jan 01 00:00:00 UTC 2013
IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.
PLoS pathogens
Schmitz I,Schneider C,Fröhlich A,Frebel H,Christ D,Leonard WJ,Sparwasser T,Oxenius A,Freigang S,Kopf M
12-1031 was used in Flow cytometry/Cell sorting to investigate the role of Foxp3+ regulatory T (Treg) cells during viral infections, showing that IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection.
Mon Dec 09 00:00:00 UTC 2013
Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance.
Journal of immunology (Baltimore, Md. : 1950)
Oderup C,LaJevic M,Butcher EC
12-1031 was used in Flow cytometry/Cell sorting to investigate the role of canonical and noncanonical Wnts in immune tolerance, showing that they program dendritic cell responses for tolerance.
Sat Jun 15 00:00:00 UTC 2013
Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo.
PloS one
Wu X,Satpathy AT,Kc W,Liu P,Murphy TL,Murphy KM
12-1031 was used in Flow cytometry/Cell sorting to investigate the role of Bcl11a in the development of dendritic cells, showing that it controls Flt3 expression in early hematopoietic progenitors and is required for pDC development.
Fri Jan 10 00:00:00 UTC 2014
Alterations in regulatory T cells induced by specific oligosaccharides improve vaccine responsiveness in mice.
PloS one
Schijf MA,Kerperien J,Bastiaans J,Szklany K,Meerding J,Hofman G,Boon L,van Wijk F,Garssen J,Van't Land B
12-1031 was used in Flow cytometry/Cell sorting to identify factors affecting the quality of the immune response to vaccination.
Tue May 27 00:00:00 UTC 2014
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.
The Journal of experimental medicine
Satpathy AT,KC W,Albring JC,Edelson BT,Kretzer NM,Bhattacharya D,Murphy TL,Murphy KM
12-1031 was used in Flow cytometry/Cell sorting to identify Zbtb46 as a transcription factor selectively expressed by classical DCs and their committed progenitors.
Mon Jun 04 00:00:00 UTC 2012
Shape-based tracking allows functional discrimination of two immune cell subsets expressing the same fluorescent tag in mouse lung explant.
PloS one
Fiole D,Touvrey C,Quesnel-Hellmann A,Douady J,Tournier JN
12-1031 was used in Flow cytometry/Cell sorting to demonstrate a novel method for discrimination between DCs and closely related cell lineages in mouse lungs.
Fri Nov 30 00:00:00 UTC 2012
Major histocompatibility complex class II expression and hemagglutinin subtype influence the infectivity of type A influenza virus for respiratory dendritic cells.
Journal of virology
Hargadon KM,Zhou H,Albrecht RA,Dodd HA,García-Sastre A,Braciale TJ
12-1031 was used in Flow cytometry/Cell sorting to show that the susceptibility of murine respiratory dendritic cell to type A influenza varies with MHC II expression and viral strain.
Tue Nov 01 00:00:00 UTC 2011
Role for E-cadherin as an inhibitory receptor on epidermal gammadelta T cells.
Journal of immunology (Baltimore, Md. : 1950)
Uchida Y,Kawai K,Ibusuki A,Kanekura T
12-1031 was used in Flow cytometry/Cell sorting to analyse functional differences between E-cadherin and α(E)β(7) integrin expressed on murine dendritic epidermal T cells.
Wed Jun 15 00:00:00 UTC 2011
Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.
PloS one
Edelson BT,Bradstreet TR,KC W,Hildner K,Herzog JW,Sim J,Russell JH,Murphy TL,Unanue ER,Murphy KM
12-1031 was used in Flow cytometry/Cell sorting to compare development of peripheral tissue dendritic cells, and susceptibility to experimental autoimmune encephalitis in GM-CSF receptor deficient mice.
Thu Mar 15 00:00:00 UTC 2012
Peripheral CD103+ dendritic cells form a unified subset developmentally related to CD8alpha+ conventional dendritic cells.
The Journal of experimental medicine
Edelson BT,KC W,Juang R,Kohyama M,Benoit LA,Klekotka PA,Moon C,Albring JC,Ise W,Michael DG,Bhattacharya D,Stappenbeck TS,Holtzman MJ,Sung SS,Murphy TL,Hildner K,Murphy KM
12-1031 was used in Flow cytometry/Cell sorting to study the relationship between nonlymphoid CD103-expressing dendritic cells (DCs) and other DC subsets.
Mon Apr 12 00:00:00 UTC 2010
Herpes simplex virus infects skin gamma delta T cells before Langerhans cells and impedes migration of infected Langerhans cells by inducing apoptosis and blocking E-cadherin downregulation.
Journal of immunology (Baltimore, Md. : 1950)
Puttur FK,Fernandez MA,White R,Roediger B,Cunningham AL,Weninger W,Jones CA
12-1031 was used in Flow cytometry/Cell sorting to identify that herpes simplex virus infection of Langerhans cells (LC) is preceded by infection of gammadelta T-cells, delaying LC migration.
Thu Jul 01 00:00:00 UTC 2010
Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.
The Journal of experimental medicine
Zhu J,Davidson TS,Wei G,Jankovic D,Cui K,Schones DE,Guo L,Zhao K,Shevach EM,Paul WE
12-1031 was used in Flow cytometry/Cell sorting to show that Gfi-1, a transcriptional repressor, has a critical role in enhancing Th2 cell expansion and repressing induction of Th17 and CD103(+) iTreg cells.
Mon Feb 16 00:00:00 UTC 2009
Optimization of methods to study pulmonary dendritic cell migration reveals distinct capacities of DC subsets to acquire soluble versus particulate antigen.
Journal of immunological methods
Jakubzick C,Helft J,Kaplan TJ,Randolph GJ
12-1031 was used in Flow cytometry/Cell sorting to investigate the best approaches to study dendritic cell migration to lung-draining lymph nodes in mice.
Mon Sep 15 00:00:00 UTC 2008
Localization of intestinal intraepithelial T lymphocytes involves regulation of alphaEbeta7 expression by transforming growth factor-beta.
International immunology
Suzuki R,Nakao A,Kanamaru Y,Okumura K,Ogawa H,Ra C
Mon Apr 01 00:00:00 UTC 2002