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PCLO Antibody (MA5-28620) in WB
Western blotting of human REH erythroid cell line lysate (1% laurylmaltoside); non-reduced sample, immunostained by Monoclonal antibody PCLO-01 (Product # MA5-28620) and goat anti-mouse IgG (H+L)-HRP conjugate. The zone evidently corresponds to a small splice variant of the PCLO protein present in this type of cell (see Uniprot database, Genome Res. 14:2121-2127(2004)); the major form (over 500 kDa) expressed in neurons is too large for analysis by Western blotting.
产品信息
MA5-28620
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
PCLO-01
抗原
Human recombinant PCLO protein
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2745579
产品详细信息
This antibody recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
靶标信息
The protein encoded by the PCLO gene is part of the presynaptic cytoskeletal matrix, which is involved in establishing active synaptic zones and in synaptic vesicle trafficking. Variations in this gene have been associated with bipolar disorder and major depressive disorder. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Aczonin; PCLO; Protein piccolo
基因别名: ACZ; KIAA0559; PCH3; PCLO
UniProt ID: (Human) Q9Y6V0
Entrez Gene ID: (Human) 27445
