Amines are derivatives of ammonia in which one or more hydrogen atoms have been replaced by an alkyl or aryl group. The breakdown of amino acids releases amines, as in the case of decaying fish, which smell of trimethylamine (structure left). In the human body, amines can be found in neurotransmitters such as epinephrine and dopamine. In nuclear power plants, morpholine and ethanolamine are amines used to minimize corrosion.
Ion-exchange chromatography with suppressed conductivity detection is a well-established method to determine μg/L to mg/L concentrations of common cations and amines. Thermo Scientific™ Reagent-Free™ Ion Chromatography (RFIC™) systems with eluent generation provide consistent separation of the analytes of interest by electrolytically generating precise and accurate eluents inline.
|Application Notes||Sample||MDL||IC Columns|
|Determination of Dimethylamine in Metformin HCl Drug Product Using IC with Suppressed Conductivity Detection (AN 298)||Pharmaceutical||1.5mg/L||Dionex IonPac CS19 Columns|
|Determination of Morpholine, Ethanolamine, and Hydrazine in Simulated Nuclear Power Plant Wastewater (AN247)||Power plant water||2.3–24.8mg/L||Dionex IonPac CS16 Columns|
|Determination of Methylamine in Drug Products (AN1057)||Pharmaceutical||1.2mg/L||Dionex IonPac CS19 Columns|
|Determination of Cations and Amines in Hydrogen Peroxide by Ion Chromatography Using a RFIC™ (Reagent-Free) System (AU 155)||Hydrogen Peroxide||0.005–0.330mg/L||Dionex IonPac CS17 Columns|