Antibodies that detect SLUG can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target SLUG in Human, Mouse, Rat and Non-human primate samples. Our SLUG monoclonal, polyclonal and...Antibodies that detect SLUG can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target SLUG in Human, Mouse, Rat and Non-human primate samples. Our SLUG monoclonal, polyclonal and recombinant...Antibodies that detect SLUG can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target SLUG in Human, Mouse, Rat and Non-human primate samples. Our SLUG monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to SLUG. Find the SLUG antibody that fits your needs. Choose from 1 of 45 SLUG antibodies, which have been validated in experiments with 128 publications and 147 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP,...
Antibodies that detect SLUG can be used in several scientific applications, including Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry and ELISA. These antibodies target SLUG in Human, Mouse, Rat and Non-human primate samples. Our SLUG monoclonal, polyclonal and recombinant monoclonal antibodies are developed in Mouse and Rabbit. These antibodies have been verified by Cell treatment and Relative expression to confirm specificity to SLUG. Find the SLUG antibody that fits your needs. Choose from 1 of 45 SLUG antibodies, which have been validated in experiments with 128 publications and 147 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, was initially identified to be involved in epithelial-mesenchymal transitions as well as the formation of the neural tube during vertebrate embryogenesis. Like Snail, Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. Once expressed, Slug will bind E-box regions of promoters and repress transcription of genes such as E-cadherin and Claudin-1. More recently, its expression in breast, esophogeal, and colorectal carcinomas has been correlated with poor prognosis for survival. Furthermore, Slug can protect hemopoietic progenitor cells from radiation-induced apoptosis by repressing the p53-mediated transcription of Puma, a BH3-only antagonist of the anti-apoptotic members of the Bcl-2 family.
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