IRAK1 Antibodies

Antibodies that detect IRAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target IRAK1 in Human, Mouse, Rat and Non-human primate samples. Our IRAK1 polyclonal,... Antibodies that detect IRAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target IRAK1 in Human, Mouse, Rat and Non-human primate samples. Our IRAK1 polyclonal, monoclonal, recombinant monoclonal... Antibodies that detect IRAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target IRAK1 in Human, Mouse, Rat and Non-human primate samples. Our IRAK1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to IRAK1. Find the IRAK1 antibody that fits your needs. Choose from 1 of 31 IRAK1 antibodies, which have been validated in experiments with 13 publications and 71 images featured in our data gallery.

Browse primary antibodies for WB, Flow,... Antibodies that detect IRAK1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and ELISA. These antibodies target IRAK1 in Human, Mouse, Rat and Non-human primate samples. Our IRAK1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Cell treatment and Knockdown to confirm specificity to IRAK1. Find the IRAK1 antibody that fits your needs. Choose from 1 of 31 IRAK1 antibodies, which have been validated in experiments with 13 publications and 71 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you're looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways. It is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation. IRAK's association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Alternatively, IRAK1 can phosphorylate TIRAP to promote its ubiquitination and subsequent degradation. IRAK1 also phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus. This results in the transcriptional activiation of type I IFN genes, which drive the cell in an antiviral state.

同义词

AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

IRAK1 Antibodies

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